Corynebacterium is a genus of Gram-positive rod-shaped bacteria. They are widely dispensed in nature and are mostly innocuous.Some are useful in highly-developed settings such as C. glutamicum. Fatty acids are building blocks for the synthesis of cell walls, which are organized with other lipids to form a permeable barrier that contributes to the natural resistance of C. jeikeium to different types of antibiotics. Another special metabolic feature in C. jeikeium is their utilization of carbohydrates. The granules are called as polar granules, infants Ernst Granules, Volutin, etc.). An enrichment medium, such as Löeffler's serum, is used to preferentially grow C. diptheriae. After that, use a selective plate known as tellurite agar, which allows all Corynebacteria (including C. diphtheriae) to reduce tellurite to metallic tellurium.
Others cause human disease such as C. diphtheriae, the pathogen responsible for diphtheria. Nondiphtherial corynebacteria, originally thought to be mainly contaminants, have recently been recognized as pathogenic, especially in immunocompromised hosts.
Corynebacteria are gram positive, catalase-positive, aerobic, mostly non-motile rods. Corynebacterium jeikeium, an opportunistic pathogen, commonly colonizes in the skin, especially in immunocompromised hosts. Because of its broad-spectrum resistance to antimicrobial agents, the susceptibility of C. jeikeium strains is studied to a wide range of antibiotics. The strains were separated into two groups depending on the susceptibility to erythromycin, with one group representing resistant organism and the other representing susceptible organisms.
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