Tacrolimus should only be given under the supervision of a doctor who is experienced in treating people who have had an organ transplant and in prescribing medications that decrease the activity of the immune system. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, and the skin condition vitiligo. Tacrolimus decreases the activity of your immune system. This may increase the risk that you will get a serious infection.
Tacrolimus belongs to a group of medicines known as immunosuppressive agents. If you experience any of the following symptoms of lymphoma, call your doctor immediately: swollen lymph nodes in the neck, armpits, or groin; weight loss; fever; night sweats; excessive tiredness or weakness; cough; trouble breathing; chest pain; or pain, swelling, or fullness in the stomach area.
Tacrolimus is used together with other medicines to prevent the body from rejecting a transplanted organ (e.g., kidney, liver, or heart). The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader. This medicine may be used with steroids, azathioprine (Imuran?), or mycophenolate mofetil (Cellcept?).
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