Saturday, March 31, 2012

Specifications of Fumonisin B2

Fumonisin B2
CAS Number: 116355-84-1
Molecular Weight: 705.8
Molecular Formula: C34H59NO14
Purity: ≥98%
Physical Appearance: White solid
Solubility: Soluble in water (25 mg/ml)
Description
Fumonisin B2 is a fumonisin mycotoxin produced by the fungi Fusarium verticillioides and Fusarium moniliforme.[1] It is a structural analog of fumonisin B1. Fumonisin B2 is added cytotoxic than fumonisin B1. Fumonisin B2 inhibits sphingosine acyltransferase.
Fumonisin B2 and added fumonisins frequently alloy maize and added crops.
Structural analog of fumonisin B1(cat no.sc-201395 and sc-201395A). Fumonisin B2 is added cytotoxic than fumonisin B1 and inhibits sphingosine acyltransferase. Fumonisin B2 and added fumonisins frequently alloy maize and added crops. A fungal metabolite produced by Fusarium moniliforme. It inhibits sphingolipid biosynthesis via inhibition of sphinganine N-acyltransferase. IC50=0.1 µM in rat alarmist microsomes.
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
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Thursday, March 29, 2012

Differences between Stannous methanesulfonate and Ethyl methanesulfonate

Stannous methanesulfonate
Synonyms: Methanesulfonic acid tin(2+) salt; Tin(II) methanesulfonate
CAS Registry Number: 53408-94-9
Formula: Sn(CH3O3S)2
Molecular Weight: 310.89
Tin(II) sulfate (SnSO4) is a actinic compound. It is a white solid that can blot abundant damp from the air to deliquesce in it, basic a solution; this acreage is accepted as deliquescence. It can be able by a displacement acknowledgment amid brownish tin and copper(II) sulfate. Tin(II) sulfate is a acceptable antecedent of tin(II) ions austere by tin(IV) species.
Character: transparent liquid of no color or light yellowish, easy to be oxidation to color yellow. The specific gravity is 1.53.
Usage: mainly being material of electric-plating and electric industry.
Ethyl methanesulfonate (EMS) is a mutagenic, teratogenic, and possibly baleful amoebic admixture with blueprint CH3SO3C2H5. It produces accidental mutations in abiogenetic actual by nucleotide substitution; decidedly by guanine alkylation. This about produces alone point mutations. It can abet mutations at a amount of 5x10-4 to 5x10-2 per gene after abundant killing. The ethyl accumulation of EMS reacts with guanine in DNA, basic the aberrant abject O-6-ethylguanine. During DNA replication, DNA polymerases that activate the action frequently abode thymine, instead of cytosine, adverse O-6-ethylguanine. Following consecutive circuit of replication, the aboriginal G:C abject brace can become an A:T pair. This changes the abiogenetic information, is generally adverse to cells, and can aftereffect in disease.
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Wednesday, March 28, 2012

What is Xanthoascin (1)?

Xanthoascin (1)
Systematic name:  Phenol, 4-[4-(3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-yl)-2,3-diisocyano-1,3-butadienyl]-
Molecular formulae:  C23H20N2O2
Molecular weight:  356
CAS:61391-08-0
Xanthoascin, a baneful metabolite afresh abandoned from rice grains infested with Aspergillus candidus L., acquired astute hepatic abrasion with jaundice in mice. It can be a applicant as a adroit abettor of primary myocardial diseases of men and contagion of foods with A. candidus and xanthoascin should be eargently examined.Xanthoascins accept alone been begin in A. candidus.
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Tuesday, March 27, 2012

Specifications of Methanesulfonyl anhydride

Methanesulfonyl anhydride
Synonyms: Mesyl anhydride; Methanesulfonic acid anhydride
CAS Registry Number: [ 7143-01-3 ]
Formula: C2H6O5S2
Molecular Weight: 174.20
Description
Appearance Light grey crystal    
Purity (%) 99.0 min.    
Methanesulfonyl chloride (%) 1.0 max.    
Iron (ppm) 10 max.    
Heavy metals (ppm) 10 max.
Methanesulfonyl anhydride is an is the acid anhydride of methanesulfonic acid. Like methanesulfonyl chloride, it may be used to generate mesylates (methanesulfonyl esters).
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Sunday, March 25, 2012

What is 2,3-Dihydroxypyridine?

2,3-Dihydroxypyridine
Synonyms: 2,3-Pyridinediol
CAS Registry Number: 16867-04-2
Formula: C5H5NO2
Molecular Weight: 111.1
2,3-Dihydroxypyridine is brown crystalline powder with Purity of 99.0 % min. Moisture is 0.5%max. Melting point is 245ºC- 248ºC(melting range less than 2)
2,3-Dihydroxypyridine is used as pharmaceutical intermediate.
2,6-Dihydroxypyridine is an alkaloid with the molecular formula C5H3N(OH)2. It is a colorless solid. 2,6-Dihyroxypyridine is an intermediate in the degradation of nicotine. 2,6-Dihydroxypyridine has been investigated in an oxidation method of dyeing hair. The process utilizes 2,6-dihydroxypyridine as a coupling agent, and 2,4,5,6-tetraaminopyrimidine as a primary intermediate. This oxidation method intensifies the color of the dyed hair for several days.
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Thursday, March 22, 2012

Specifications of 2-Chloro-3-cyanopyridine

2-Chloro-3-cyanopyridine
Synonyms 2-Chloronicotinonitrile; 3-Cyano-2-chloropyridine
Molecular Formula C6H3ClN2
Molecular Weight 138.56
CAS Registry Number 6602-54-6
Description of 2-Chloro-3-cyanopyridine
Appearance: White to slight yellow crystalline powder
Storage : Preserve in tight dry ray-resistant containers
Purity (%) 99.0 min.
Moisture (%) 0.5 max.
Melting point (°C) 105 - 108 (melting range less than 2) 
2-Chloro-3-cyanopyridine is used for pharmaceutical intermediate and packed  in 25 kg net in carton drum.
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What is Phloroglucinol used for?

Phloroglucinol is a benzenetriol. It is an organic compound that is used in the synthesis of pharmaceuticals and explosives. This molecule exists in two forms, or tautomers, 1,3,5-trihydroxybenzene, which has phenol-like, and 1,3,5-cyclohexanetrione (phloroglucin), which has ketone-like character. These two tautomers are in equilibrium. Phloroglucinol is a useful intermediate because it is polyfunctional.
Phloroglucinols occur naturally in certain plant species. For example, they (and sometimes their acyl dervatives) are present in the fronds of the coastal woodfern, Dryopteris arguta. Brown algae also produce phloroglucinol derivatives known as phlorotannins.
Applications
Phloroglucinol is mainly used as a coupling agent in printing. It links diazo dyes to give a fast black.
It is useful for the industrial synthesis of pharmaceuticals and explosives. It is also used as a treatment for gallstones, spasmodic pain and other related gastrointestinal disorders. It has a non-specific spasmolytic action on the vessels, bronchi, intestine, ureters and gall bladder, and is used for treating disorders of these organs.
Phloroglucinolysis is an analytical technique to study condensed tannins by mean of depolymerisation. The reaction makes use of phloroglucinol as nucleophile.
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Wednesday, March 21, 2012

What is Regatin A?

Regatin A
Systematic name:3(2H)-Furanone, 2-(1E,3E)-1,3-hexadienyl-5-methoxy-2-methyl-4-[(2E)-1-oxo-2-butenyl]-, (-)-
Molecular formulae:C16H20O4
Molecular weight:276
Cas number: 65794-79-8
Regatin A (Fig. 1A) which is produced by Phialophora gregata (Allington and Chamberlain) W. Gams, is an enantiomer of aspertetronin A (Fig. 1B), which is a accepted metabolite from cultures of Aspergillus rugulosus.
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Descriptions of Antimicrobial Metabolite 1

Description of Antimicrobial Metabolite 1
Absolute configuration of keisslone, a new antimicrobial metabolite from Keissleriella sp. YS4108, a marine filamentous fungus.
Cas number:89367-83-9
Formula: C15H10O5
An antimicrobial is a substance that kills or inhibits the growth of microorganisms such as bacteria, fungi, or protozoans. Antimicrobial drugs either kill microbes (microbiocidal) or prevent the growth of microbes (microbiostatic). Disinfectants are antimicrobial substances used on non-living objects or outside the body.
The antimicrobial properties of 21 plant essential oils and two essences were investigated against five food-borne pathogens, Campylobacter jejuni, Salmonella enteriditis, Escherichia coli, Staphylococus aureus and Listeria monocytogenes. The oils of bay, cinnamon, clove and thyme were the most inhibitory, each having a bacteriostatic concentration of 0.075% or less against all five pathogens.
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Tuesday, March 20, 2012

Applications of 4-Aminopyridine

4-Aminopyridine (INN fampridine, USAN dalfampridine) is an organic compound with the chemical formula C5H4N–NH2. The molecule is one of the three isomeric amines of pyridine. It is used primarily as a research tool, in characterizing subtypes of potassium channel, and has also been used to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease. The drug has orphan drug status in the United States under the trade name Neurelan. It was undergoing Phase III clinical trials as of 2008, and the U.S. Food and Drug Administration (FDA) approved the compound on January 22, 2010. Fampridine is also marketed as Ampyra (pronounced "am-PEER-ah," according to the maker's website) in the United States by Acorda Therapeutics and as Fampyra in Europe.
Applications
The largest scale industrial application of 4-Aminopyridine is as a precursor to the drug pinacidil, which affects potassium ion channels.
In the laboratory, 4-AP is a useful pharmacological tool in studying various potassium conductances in physiology and biophysics. It is a relatively selective blocker of members of Kv1 (Shaker, KCNA) family of voltage-activated K+ channels. At concentration of 1 mM it selectively and reversibly inhibits Shaker channels without significant effect on other sodium, calcium, and potassium conductances.
4-Aminopyridine is also used as a bird control agent, under the trade name Avitrol; it causes convulsions and typically death, depending on dosage. The use of 4-aminopyridine in bird control has been criticized by the Humane Society of the United States.
Medical use
Fampridine has been used clinically in Lambert-Eaton myasthenic syndrome and multiple sclerosis. It acts by blocking potassium channels, prolonging action potentials and thereby increasing neurotransmitter release at the neuromuscular junction. The drug has been shown to reverse tetrodotoxin toxicity in animal experiments.
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How to get Diphenolic acid?


Diphenolic acid
Synonyms: 4,4-Bis(4-hydroxyphenyl)pentanoic acid; 4,4'-Bis(4-hydroxyphenyl)valeric acid; CTFA
CAS Registry Number: 126-00-1
Formula: C17H18O4
Molecular Weight: 286.32
Diphenolic acerbic is a carboxylic acerbic with atomic blueprint C17H18O4. Its IUPAC name is 4,4-bis(p-hydroxyphenyl)pentanoic acid, and it can be able by the abstract acknowledgment of phenol with levulinic acerbic in the attendance of hydrochloric acid.
Diphenolic acid is a solid at room temperature, melting at 168–171 °C and boiling at 507 °C. According to its MSDS, diphenolic acid is soluble in ethanol, isopropanol, acetone, acetic acid, and methyl ethyl ketone, but insoluble in benzene, carbon tetrachloride, and xylene.
Diphenolic acid may be a suitable replacement for bisphenol A as a plasticizer.
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Monday, March 19, 2012

What is Warfarin metabolite 2?

Warfarin metabolite 2
Systematic name 2,5-Hexanedione, 1-hydroxy-1-(2-oxo-3,5-cyclohexadien-1-ylidene)-3-phenyl-, (E)-
Molecular formulae:  C18H16O4
Molecular weight:  296
CAS:119465-34-8
Warfarin metabolites,Stereochemical aspects of protein binding and displacement by phenylbutazone.Warfarin metabolism may be inhibited through drug-drug interactions, including amiodarone and statins.
Warfarin is an oral anticoagulant that inhibits the synthesis of clotting factors, thus preventing blood clot formation. Blood clots can occur in the veins of the lower extremities, usually after periods of immobility. These clots can break off and become lodged in the blood vessels of the lung (pulmonary embolism), causing shortness of breath, chest pain, and even life-threatening shock. Blood clots can also occur in the atria of the heart during atrial fibrillation, and around artificial heart valves. One of these clots can also break off and obstruct a blood vessel in the brain, causing an embolic stroke with paralysis. Coumadin is important in preventing the formation of blood clots. It is also important to prevent extension of clots already formed, and to minimize the risk of blood clot embolization to other vital organs such as the lungs and brain.
Warfarin is used in treating patients with blood clots in the lower extremities to prevent extension of the clot, and to reduce the risk of pulmonary embolism. Patients with pulmonary embolism are treated with Coumadin to prevent further blood clot emboli. Coumadin is also used in patients with atrial fibrillation and artificial heart valves to reduce the risk of strokes. It is also helpful in preventing blood clot formation in certain orthopedic surgeries such as knee or hip replacements. Coumadin is also used in preventing blood clot closure of coronary artery stents.
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Sunday, March 18, 2012

Specifications of 3-Hydroxypyridine

3-Hydroxypyridine
CAS No.:  109-00-2
Formula: C5H5NO
Molecular Weight: 95.1
3-Hydroxypyridine is also called 3-Pyridinol, 3-Hydroxypyridine is yellow to brownish crystal. Its Purity is 99.0% min. Moisture is 0.5% max. Sulfate ash is 0.5% max. Melting point of 3-Hydroxypyridine is 124°C - 127 °C.
3-Hydroxypyridine is used as pharmaceutical intermediate and packed in  25 kg net in carton drum.
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Thursday, March 15, 2012

Properties of Silica gel

Silica gel
is a granular, vitreous, absorptive anatomy of silicon dioxide fabricated synthetically from sodium silicate. Despite its name, silica gel is a solid. It is a by itself occurring mineral that is antiseptic and candy into either diminutive or beaded form. As a desiccant, it has an boilerplate pore admeasurement of 2.4 nanometers and has a able affection for baptize molecules.
Silica gel is a lot of frequently encountered in accustomed activity as chaplet in a baby (typically 2 cm x 3 cm) cardboard packet. In this form, it is acclimated as a anhydrous to ascendancy bounded clamminess in adjustment to abstain accident or abasement of some goods. Because of poisonous dopants (see below) and their actual top assimilation of moisture, silica gel packets usually buck warnings for the user not to eat the contents.
Properties
Silica gel's top apparent breadth (around 800 m²/g) allows it to blot baptize readily, authoritative it advantageous as a anhydrous (drying agent). Once saturated with water, the gel can be regenerated by heating it to 120 °C (250 °F) for two hours. Some types of silica gel will "pop" if apparent to abundant water. This is acquired by accident of the silica spheres if contacting the water.
Uses
Silica gel may aswell be acclimated to accumulate the about clamminess (RH) central a top abundance radio or digital manual arrangement waveguide as low as accessible (see aswell Clamminess buffering). Excessive damp accretion aural a waveguide can could cause arcing central the waveguide itself, damaging the ability amplifier agriculture it. Also, the chaplet of baptize that anatomy and abbreviate central the waveguide change the appropriate impedance and frequency, aspersing the signal. It is accepted for a baby aeroembolism air arrangement (similar to a baby home aquarium pump) to be active to broadcast the air central the waveguide over a jar of silica gel.
Silica gel is aswell acclimated to dry the air in automated aeroembolism air systems. Air from the compressor acquittal flows through a bed of silica gel beads. The silica gel absorbs damp from the air, preventing accident at the point of use of the aeroembolism air due to abstract or moisture. The aforementioned arrangement is acclimated to dry the aeroembolism air on railway locomotives, area abstract and ice in the anchor air pipes can advance to anchor failure.
Silica gel is sometimes acclimated as a canning apparatus to ascendancy about clamminess in building and library exhibitions and storage.
Other applications cover analytic analysis strips, assimilation devices, syringes, biologic analysis kits and hospital sanitation kits.More about: Silica gel sale
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Wednesday, March 14, 2012

What is Terreic acid?

Description of Terreic acid
Terreic acid is a metabolite that displays antibiotic properties. It has been found to covalently inhibit UDP-N-Acetylglucosamine 1-Carboxyvinyltransferase (MurA), a bacterial cell wall biosynthetic enzyme. It has also been found to inhibit the catalytic activity of Bruton’s tyrosine kinase (BTK) and the interaction of BTK with protein kinase C beta type (PKCβII) without affecting the activity of PKC. Terreic acid is useful to study BTK’s role in cellular signaling.
Biological Activity
Selective inhibitor of Bruton's tyrosine kinase (BTK). Inhibits the interaction between PKCbII and BTK (IC50 ~ 30 mM) and the catalytic activity of BTK but does not affect the activity of PKC. Has little effect on the activities of Lyn, Syk, PKA, casein kinase I, ERK1, ERK2 and p38 kinases.
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Tuesday, March 13, 2012

What is Diphenolic acid?

Diphenolic acid is a carboxylic acid with molecular formula C17H18O4. Its IUPAC name is 4,4-bis(p-hydroxyphenyl)pentanoic acid, and it can be prepared by the condensation reaction of phenol with levulinic acid in the presence of hydrochloric acid. The equation for this synthesis is: 2 C6H5OH + CH3C(O)CH2CH2COOH → CH3C(p-C6H4OH)2CH2CH2COOH + H2O
Diphenolic acid is a solid at room temperature, melting at 168–171 °C and boiling at 507 °C. According to its MSDS, diphenolic acid is soluble in ethanol, isopropanol, acetone, acetic acid, and methyl ethyl ketone, but insoluble in benzene, carbon tetrachloride, and xylene.
Diphenolic acid may be a suitable replacement for bisphenol A as a plasticizer
Application 
Used to prepare various kinds of synthetic resins, electrophoretic coatings, glossy printing inks and coatings etc. 
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Monday, March 12, 2012

What is Aflatoxin B1?

Aflatoxins are naturally occurring mycotoxins that are produced by many species of Aspergillus, a fungus, the most notable ones being Aspergillus flavus and Aspergillus parasiticus. Their name is derived from the early work that discovered Aspergillus Flavus toxins. Aflatoxins are toxic and among the most carcinogenic substances known. After entering the body, aflatoxins may be metabolized by the liver to a reactive epoxide intermediate or hydroxylated to become the less harmful aflatoxin M1.
Aflatoxin B1 is derived from both a dedicated fatty acid synthase (FAS) and a polyketide synthase (PKS), together known as norsolorinic acid synthase. The biosynthesis begins with the synthesis of hexanoate by the FAS, which then becomes the starter unit for the iterative type I PKS. The PKS adds seven malonyl-CoA extenders to the hexanoate to form the C20 polyketide compound. The PKS folds the polyketide in a particular way to induce cyclization to form the anthraquinone norsolorinic acid. A reductase(E1) then catalyzes the reduction of the ketone on the norsolorinic acid side-chain to yield averantin. Averantin is converted to averufin via a two different enzymes, a hydroxylase (E2) and an alcohol dehydrogenase (E3). This will oxygenate and cyclize averantin's side chain to form the ketal in averufin.
From this point on the biosynthetic pathway of aflatoxin B1 becomes much more complicated, with several major skeletal changes. Most of the enzymes have not been characterized and there may be several more intermediates that are still unknown. However, what is known is that averufin is oxidized by a P450-oxidase, AvfA (E4), in a Baeyer-Villiger oxidation. This opens the ether rings and upon rearrangement versiconal acetate is formed. Now an esterase, EstA (E5), catalyzes the hydrolysis of the acetyl, forming the primary alcohol in versiconal. The acetal in versicolorin A is formed from the cyclization of the side-chain in versiconal, which is catalyzed by VERB synthase (E6), and then VerB, a desaturase (E7), reduces versicolorin B to form the dihydrobisfuran.
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Sunday, March 11, 2012

What is 2-Pyridylethylamine?

2-Pyridylethylamine is a histamine agonist which is selective for the H1 subtype.
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes.
Betahistine is an example used to treat vertigo.
Betazole and impromidine are examples used in diagnostics.
2-Pyridylethylamine is also called 2-Aminoethylpyridine, 2-Pyridineethanamine or 2-(2-Aminoethyl)pyridine. Its Molecular Formula is C7H10N2. Molecular Weight is 122.17. CAS Registry Number is 2706-56-1. 2-Pyridylethylamine is used as a selective histamine H1-receptor agonist.
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Thursday, March 8, 2012

What is Methanesulfonyl anhydride?

Methanesulfonyl anhydride
Synonyms: Mesyl anhydride; Methanesulfonic acerbic anhydride
CAS No.:7143-01-3
Molecular Formula: C2H6O5S2
Molecular Weight: 174.20
Specifications
Appearance Light blah clear
Purity (%) 99.0 min.
Methanesulfonyl chloride (%) 1.0 max.
Iron (ppm) 10 max.
Heavy metals (ppm) 10 max.
Applicaton
Methanesulfonic anhydride is used as reagent.
Packaging
100 kg net per drum.
Methanesulfonyl anhydride is an is the acerbic anhydride of methanesulfonic acid. Like methanesulfonyl chloride, it may be acclimated to accomplish mesylates (methanesulfonyl esters).
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Wednesday, March 7, 2012

What is Ochratoxin C?

Ochratoxins are a accumulation of mycotoxins produced by some Aspergillus breed (mainly A. ochraceus, but aswell by 33% of A. niger automated strains) and some Penicillium species, abnormally P. verrucosum and P. carbonarius . Ochratoxin A is the a lot of accustomed and accordant fungal adulteration of this group, while ochratoxins B and C are of bottom importance.
Ochratoxin A is accepted to action in bolt such as cereals, coffee, broiled bake-apple and red wine. It is advised a animal carcinogen and is of appropriate absorption as it can be accumulated in the meat of animals. Thus meat and meat articles can be attenuated with this toxin. Exposure to ochratoxins through diet can accept can astute toxicity to beastly kidneys, and may be carcinogenic.
Ochratoxins are accepted compounds. They are baneful metabolites accepted to be produced from some strains of the bane Aspergillus ochraceus. Interest in the ochratoxins, and decidedly ochratoxins A, B and C, is prompted by the bloom hazard theypose because of their accident in agronomical articles such as silage, hay, feedstuffs and corn. Ochratoxin A is the above ochratoxin basic and is the a lot of toxic. Ochratoxin C is about according in toxicity while ochratoxin B is about 1/10th as toxic.
Ochratoxins are a baby accumulation of chemically accompanying baneful fungal metabolites (mycotoxins) produced by assertive moulds of the genera Aspergillus and Penicillium growing on a advanced ambit of raw aliment commodities. Some ochratoxins are almighty toxins and their attendance in aliment is undesirable.
The ochratoxins are pentaketides fabricated up of dihydro-isocoumarin affiliated to ß-phenylalanine. The a lot of important and a lot of baneful ochratoxin begin by itself in aliment is ochratoxin A (OTA). The alone added ochratoxin begin in aliment is ochratoxin B, which is attenuate and abundant beneath toxic. Added structurally accompanying ochratoxins cover ochratoxin C, a and ß. These accept been abandoned from fungal cultures, but are not commonly begin in foods. The butt of this area accordingly refers accurately to OTA.
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What is Ethyl-N-methyl malonamide?

Ethyl-N-methyl malonamide is also called N-Methyl-malonamic acerbic ethyl ester or 3-(Methylamino)-3-oxo-propanoic acerbic ethyl ester. Ethyl-N-methyl malonamide is a white bright or achromatic bright aqueous with a purity of 90.0% min and Moisture of 0.5% max. Ethyl-N-methyl malonamide is used as biologic intermediate. Ethyl-N-methyl malonamide is Packed
25 kg net in PE drums.
Specifications
CAS No.: 71510-95-7
Formula: C6H11NO3
Molecular Weight: 145.16
Melting point (°C) 34 - 35
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Monday, March 5, 2012

What is Isodihydroauroglaucin 1?

Isodihydroauroglaucin 1
Systematic name:Benzaldehyde, 2-(5E)-5-heptenyl-3,6-dihydroxy-5-(3-methyl-2-butenyl)-
Molecular formulae :C19H26O3
Molecular weight:302
Chemical abstracts number:74886-32-1
Isodihydroauroglaucin 1 inhibited HeLa cell growth, its IC50 value was about 170 μmol·L-1; results from DNA content analysis and Annexin V-FITC/PI dual staining assays showed that isodihydroauroglaucin induced apoptosis of HeLa cells; isodihydroauroglaucin induced DNA damage in HeLa cells.
Isodihydroauroglaucin may induce apoptotic cell death by inducing DNA damage.
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Sunday, March 4, 2012

What is Levulinic acid used for?

Levulinic acid, or 4-oxopentanoic acid, is an organic compound with the formula CH3C(O)CH2CH2CO2H. It is a keto acid. This white crystalline is soluble in water, ethanol, and diethyl ether.
Uses
Related to its original synthesis, levulinic acid is prepared in the laboratory by heating sucrose with concentrated hydrochloric acid.[3] The process proceeds via the intermediacy of glucose, which is isomerized to fructose and then hydroxymethylfurfural. Other sugar-derivatives - e.g., levulose(=D-fructose), inulin, starch - and other acids - e.g., sulfuric acids - can be used.
Levulinic acid is a potential precursor to nylon-like polymers, synthetic rubbers, and plastics. It is a versatile synthetic intermediate, e.g., in the synthesis of pharmaceuticals. It is a precursor in the industrial production of other chemical commodities such as methyltetrahydrofuran, valerolactone, and ethyl levulinate.
Levulinic acid is also a photosensitizer for photodynamic therapy.
Levulinic acid is used in cigarettes to increase nicotine delivery in smoke and binding of nicotine to neural receptors.
Safety
Levulinic acid is relatively nontoxic, with an LD50 of 1850 mg/kg.
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Thursday, March 1, 2012

Specifications of 2,3-Dihydroxypyridine

2,3-Dihydroxypyridine
Synonyms: 2,3-Pyridinediol
CAS Registry Number: 16867-04-2
Formula: C5H5NO2
Molecular Weight: 111.1
Specifications          
Appearance Brown crystalline powder    
Purity (%) 99.0 min.    
Moisture (%) 0.5 max.    
Melting point (ºC) 245 - 248 (melting range less than 2)
More Information of 2,3-Dihydroxypyridine 
Pharmaceutical intermediate.
Packaging  
25/200 kg net in carton drums.
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