What is Warfarin metabolite 3?

Warfarin metabolite 3
Systematic name:  2H-Pyran-3(4H)-one, dihydro-6-hydroxy-6-methyl-2-(2-oxo-3,5-cyclohexadien-1-ylidene)-4-phenyl-
Molecular formulae:  C18H16O4
Molecular weight:  296
CAS:119465-35-9
Description of Warfarin metabolite 3
Control of rats and mice. Commercial baits are usually in a concentration of 0.02% warfarin. They may be formulated as corn-meal or oats, or other grains. There is no tendency to bait shyness. Warfarin is no longer popular as a rodenticide because rats and mice have become resistant (Tomlin, 1994).
It is available as the sodium salt of the racemic mixture for use as an anticoagulant, in oral doses of 2 to 25 mg daily.
Uses
Anticoagulant rodenticide.
Therapeutic anticoagulant.
Warfarin metabolites are less bound both within plasma and a 40 g/liter solution of human serum albumin than the enantiomers of warfarin. The reduced warfarin metabolites have a lower fraction unbound [1.33% for (S,R)-WA, 2.09% for (S,S)-WA, and 1.04% for (R,S)-WA] than hydroxylated metabolites [3.24% for (R)-6-HW, 4.26% (S)-6-HW, 4.49% for (R)-7-HW and 4.27% for (S)-7-HW] to HSA. Phenylbutazone produced a concentration-dependent increase in the unbound fraction of all metabolites. It was possible to predict the unbound fraction of warfarin metabolites based on the unbound fraction of warfarin enantiomers. © 1993 Wiley-Liss, Inc.
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