Tacrolimus (also FK-506 or fujimycin, trade names Prograf, Advagraf, Protopic) is an immunosuppressive drug that is mainly used after allogeneic organ transplant to reduce the activity of the patient's immune system and so lower the risk of organ rejection. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, and the skin condition vitiligo.
Tacrolimus lowers the body's ability to fight an infection/disease (immunosuppression). This may increase your risk of development an infection or dependable types of cancer (e.g., skin cancer, lymphoma). To reduce the risk of these serious side effects, take this medicament at the most crushed competent Lucy in the sky with diamonds when guided by your doctor. Keep all medical and laboratory designations.
The macrolides are a group of drugs (typically antibiotics) whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. Macrolides belong to the polyketide class of natural products.
Tacrolimus comes as a capsule to take by mouth. It equals usually called for twice a day. Space your doses 12 hours apart, and take tacrolimus at the same times every day. Follow the directions on your prescription label carefully, and necessitate your medico or pharmacist to explain any part you do not understand. Take tacrolimus exactly as directed. Do not take more or less ofaimor tnumerousit more often than prescribed by your doctor.
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